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Mutations in Apolipoprotein A-II Gene (APOA2) MIM +107670
 
NCBI Reference Sequences:
 
Location: 1q23.3  
Protein: ACCESSION NP_001634.1
mRNA: ACCESSION NM_001643.1
Genomic DNA: ACCESSION NG_012043
 
APOA2 exons 1 to 4 4 mutations associated with amyloidosis, all affecting the stop codon
 
cDNA No.
1
ATG
AAG
CTG
CTC
GCA
GCA
ACT
GTG
CTA
CTC
CTC
M
K
L
L
A
A
T
V
L
L
L
-
34
ACC
ATC
TGC
AGC
CTT
GAA
GGA
GCT
TTG
GTT
CGG
T
I
C
S
L
E
G
A
L
V
R
-
67
AGA
CAG
GCA
AAG
GAG
CCA
TGT
GTG
GAG
AGC
CTG
R
Q
A
K
E
P
C
V
E
S
L
-
100
GTT
TCT
CAG
TAC
TTC
CAG
ACC
GTG
ACT
GAC
TAT
V
S
Q
Y
F
Q
T
V
T
D
Y
-
134
GGC
AAG
GAC
CTG
ATG
GAG
AAG
GTC
AAG
AGC
CCA
G
K
D
L
M
E
K
V
K
S
P
-
167
GAG
CTT
CAG
GCC
GAG
GCC
AAG
TCT
TAC
TTT
GAA
E
L
Q
A
E
A
K
S
Y
F
E
-
200
AAG
TCA
AAG
GAG
CAG
CTG
ACA
CCC
CTG
ATC
AAG
K
S
K
E
Q
L
T
P
L
I
K
-
234
AAG
GCT
GGA
ACG
GAA
CTG
GTT
AAC
TTC
TTG
AGC
K
A
G
T
E
L
V
N
F
L
S
-
267
TAT
TTC
GTG
GAA
CTT
GGA
ACA
CAG
CCT
GCC
ACC
Y
F
V
E
L
G
T
Q
P
A
T
-
G/.....
C/AC......
300
CAG
TGA
Q